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| Anabolic
steroid alternatives
What
are anabolic steroids?
Anabolic steroids" is the familiar name for synthetic substances
related to the male sex hormones (androgens). They promote the growth
of skeletal muscle (anabolic effects) and the development of male sexual
characteristics (androgenic effects), and also have some other effects.
The term "anabolic steroids" will be used through-out this report
because of its familiarity, although the proper term for these compounds
is "anabolic-androgenic" steroids.
Anabolic steroids were developed in the late 1930s primarily to treat
hypogonadism, a condition in which the testes do not produce sufficient
testosterone for normal growth, development, and sexual functioning. The
primary medical uses of these compounds are to treat delayed puberty,
some types of impotence, and wasting of the body caused by HIV infection
or other diseases.
During the 1930s, scientists discovered that anabolic steroids could facilitate
the growth of skeletal muscle in laboratory animals, which led to use
of the compounds first by bodybuilders and weightlifters and then by athletes
in other sports. Steroid abuse has become so widespread in athletics that
it affects the outcome of sports contests.
More than 100 different anabolic steroids have been developed, but they
require a prescription to be used legally in the United States. Most steroids
that are used illegally are smuggled in from other countries, illegally
diverted from U.S. pharmacies, or synthesized in clandestine laboratories.
What are steroid alternatives?
19-norandrostenedione is the nandrolone equivalent of androstenedione.
It is an efficient precursor to its active steroid form, and overall is
considered nothing short of a well-proven anabolic. Although like androstenedione
this hormone is open to estrogen conversion in its initial state, the
tendency for 19-nor steroids to interact with the necessary enzyme is
very low. We therefore see very few reported problems with water/fat retention
and gynecomastia, even when this supplement is taken in heavier cycles.
Most users report a solid gain of muscle mass, typically with an accompanying
loss of body fat and increased visibility.
Using the transdermal product
DermaGAIN by Impact Nutrition is a particularly advantageous way of
administering this hormone actually
DermaGAIN contains a combination of both this and the following nandrolone
precursors), as this method of delivery bypasses the first pass by the
liver that can deactivate greater than 90% of the ingested hormone. Transdermal
deliver allows for near total absorption of the compound into the blood
stream. Impact additionally uses DIM (diindolylmethane) in this product,
and anti-estrogenic substance that works by enhancing the metabolic breakdown
of estrogens. Though it may seem unneeded, it was added as a protective
measure to combat the actions of any minimal estrogen buildup that could
possibly result.
19-nor 4-androstenediol:
Like 4-androstenediol, this prohormone utilizes a more active enzyme in
its biotransformation to the steroid nandrolone. It is therefore slightly
more potent in comparison to 19-norandrostenedione, however both of these
two nandrolone precursors are considered solidly effective anabolics.
Only those extremely sensitive to estrogen or using unusually high amounts
will likely ever notice a difference in estrogen conversion rates, although
technically this prohormone would be more suitable in this regard as it
avoids any possible direct path of conversion (the same trait noted with
4-androstenediol). Otherwise these two precursors are really interchangeable.
Combining these two prohormones (as in
DermaGAIN) actually seems to be the most advantageous method of taking
nandrolone precursors, as this utilizes two distinct paths of metabolism
for the optimal buildup of active steroid in the blood stream.
19-nor 5-androstenediol:
This prohormone is a 19-nor form of 5-androstenediol. While we don't have
much to report about 5androstenediol, there is even less to report about
this compound. Its conversion rate to nandrolone is low, and there likewise
seems to be little in terms of positive feedback. It seems to be more
the product of a clear manufacturing opportunity than of research and
successful application. Some may find a use for this compound, but it
is clearly not the efficient nandrolone precursor we see in 19-nor 4-androstenediol.
1,4-androstadiene-3-one,17b-ol:
Boldenone is a popular anabolic steroid, manufactured as boldenone undecylenate
in several veterinary drug preparations including Ganabol, Equipoise,
Ultragan, Maxigan and Equi-gan. Structurally boldenone (1,4-androstadiene-3-one,17b-ol)
is a close derivative of testosterone (4-androstene-3-one,17b-ol), differing
from this androgen only by the addition of a second double bond in the
A-ring of the structure (between carbons one and two). Likewise its direct
precursor 1,4-androstadienedione differs from testosterone's direct precursor
4-androstenedione only by this same alteration, and converts to active
form via the same widely distributed body enzyme (17-beta hydroxysteroid
dehydrogenase, which interconverts these hormones between inactive 17-keto
and active 17-beta hydroxy form). Very effective for increasing RBC blood
plasma levels, enhancing recovery, and overall muscle growth.
Equi-bolan by Impact Nutrition is an oral steroidal precursor to boldenone.
5-alpha androstanediol:
Maxteron (5-alpha androstanediol) is the first dihydrotestosterone
(DHT) prohormone to be developed. DHT is typically thought of as a side
effect hormone, however this is more a product of misunderstanding than
fact. In the human body DHT is much more active than testosterone, and
is produced locally in tissues sensitive to androgen action such as the
prostate, skin, scalp and certain areas of the central nervous system.
It is for this reason that its presence is usually associated with side
effects, however it activates the same cellular receptor that testosterone
does. The applications for a DHT prohormone are actually quite numerous,
as it represents the only truly non-aromatizable (will not convert to
estrogen)
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